NANO TECHNOLOGY:

NANO TECHNOLOGY: "Nanotechnology is used to create ultra-small polymer particles capable of carrying the drugs into the body. The scientists say the development of the combination drug makes it possible to create a precise feedback system that can safely regulate release of the drugs aboard the nanoparticles

Using human plasma in laboratory tests, one ‘pro drug’ was successfully identified as being able to sense oxygen blood levels and turned on or off as needed.

“When respiratory distress is too severe, that will trigger release of Naloxone, the antagonist (morphine-suppressing) drug. When the oxygen blood levels go up, that will stop the action of the antagonist drug and more morphine will be available,” says Baohua Huang, Ph.D., the study’s first author and a research investigator at the Michigan Nanotechnology Institute and in Internal Medicine.

MNIMBS scientists are conducting further extensive studies before testing on humans proceeds."